MEASURING bacterial ADHESION AT THE CELL LEVEL.
SINGLE bacteria ADHESION
Measuring bacterial adhesion at single cell level is now possible thanks to FluidFM. Quantify anti-microbial surfaces, gain insight into pathogen pathways, or explore your own unique application. FluidFM technology gives you access to new realms of the microbiological domain.
An S. pyogenes cell (highlighted in blue) is detached from the surface using a FluidFM probe cantilever. The outlines of the pyrimde can be seen around the cell. Courtesy of Potthoff E., ETH Zurich.
NO OTHER METHOD
POINT & CLICK
Yeast cells are arranged in a row via pick and place.
a Shorter Handling Time.
The target cell is selected via the point and click interface and then reversibly attached to the FluidFM probe by applying an underpressure. It is subsequently detached from the surface by retracting the measurement probe, and the resulting adhesion forces are precisely recorded with pN resolution. All force curves are automatically stored and organized for analysis using our advanced data analysis software or custom third-party tools.
2015. E. Potthoff, D. Ossola, T. Zambelli & J. A. Vorholt.
Bacterial adhesion force quantification by fluidic force microscopy.
Nanoscale, 7 (9), 4070 – 4079. doi:10.1039/c4nr06495j