MEASURING BACTERIAL ADHESION AT THE CELL LEVEL.
SINGLE BACTERIA ADHESION
DISCOVER NEW POSSIBILITIES.
Enjoy the unique opportunity to measure the adhesion of individual bacteria.
Measuring bacterial adhesion at single cell level is now possible thanks to FluidFM. Quantify anti-microbial surfaces, gain insight into pathogen pathways, or explore your own unique application. FluidFM technology gives you access to new realms of the microbiological domain.
NO OTHER METHOD
POINT & CLICK
A SHORTER HANDLING TIME.
The short preparation time in combination with reusable measurement probes makes FluidFM the perfect tool for all your single bacteria adhesion studies.
The target cell is selected via the point and click interface and then reversibly attached to the FluidFM probe by applying an underpressure. It is subsequently detached from the surface by retracting the measurement probe, and the resulting adhesion forces are precisely recorded with pN resolution. All force curves are automatically stored and organized for analysis using our advanced data analysis software or custom third-party tools.
K. S. Sprecher, I. Hug, J. Nesper, E. Potthoff, M. A. Mahi, M. Sangermani, V. Kaever, T. Schwede, J. Vorholt, U. Jenal. Cohesive Properties of the Caulobacter crescentus Holdfast Adhesin Are Regulated by a Novel c-di-GMP Effector Protein. mBio (American Society for Miobiology) 8(2). doi: 10.1128/mBio.00294-17
J.S. McGrath, J. Quist, J.R.T. Seddon, S.C.S. Lai, S.G. Lemay & H.L. Bridle. Deformability Assessment of Waterborne Protozoa Using a Microfluidic-Enabled Force Microscopy Probe. PLOS ONE, 11(3), e0150438. doi:10.1371/journal.pone.0150438
E. Potthoff, D. Ossola, T. Zambelli & J. A. Vorholt. Bacterial adhesion force quantification by fluidic force microscopy. Nanoscale, 7 (9), 4070 – 4079. doi:10.1039/c4nr06495j