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2. CYTOSURGE AG, SÄGEREISTRASSE 25, 8152 GLATTBRUGG, SWITZERLAND PHONE +41 44 533 14 50, FAX +41 44 533 14 59, WWW.CYTOSURGE.COM CONTACT US. We offer complete support for our customers and distributors. Please visit the Cytosurge Help Center in order to access the FluidFM ® user community. www.fluidfm.com Subject to change without notice. Revision: 1.7 ID: CYTO-14-48 Copyright © 2016 Cytosurge AG, Switzerland EASY. • Intuitive point and click interface • No prior knowledge required • Works with standard multiwell plates • Cells can be approached quickly and automatically over the entire sample area The FluidFM BOT is engineered to work seamlessly toge- ther with standard inverted light microscopes. Every aspect of the instrument has been carefully devised to give you ac - cess to a whole world of new applications for your research in life sciences, material sciences, physics, and beyond. The FluidFM BOT system meshes well with your existing lab routines. Compatibility with standard multiwell plates, petri dishes, and microscopy slides ensures proper integration with existing downstream analysis techniques. By supporting two multiwell plates, the system boosts your productivity by minimizing laborious sample swapping. In combination with fully automated probe exchange and probe washing features, the system allows for a tenfold increase in throughput for most established FluidFM ap - plications. By minimizing manual intervention during mea - surements, all experiments are executed in a clean and precise fashion and your samples remain immaculate for long periods. High levels of automation ensure maximum repro - ducibility of your results, even with different operators. FAST. • Automatic loading and washing of FluidFM probes • Up to tenfold throughput for established FluidFM experiments • Simultaneous use of several sample containers – no time lost due to swapping containers AUTOMATED. • Sound statistics in a short time • Clean experiments – no manual intervention is necessary • High reproducibility through auto- mation, even among different users • Highly accurate force curves, especially for mammalian cells (100+ μm) F luid FM ® BOT – FULLY INTEGRATED SYSTEM SOLUTION. Thanks to the sophisticated XY-sample-positioning tech - nology, the FluidFM BOT gives you access to vast sample areas with unmatched repositioning precision at the nano - meter scale over the full range. The revolutionary Z-positioning stage means highly precise force measurements over distances of up to 6 cm are now possible. Previously challenging and complex studies such as cell-cell interaction are simple thanks to the unmatched measurement range. The FluidFM BOT allows you to focus on your experimental design instead of limiting instrument specifications. A high level of automation coupled with intelligent and intuitive instrument operation allows many data points to be gathe - red within a short timeframe. Collect strong statistics and increase confidence in your experimental results with the FluidFM BOT. Automation, functional design, and intuitive operation via the award win - ning FluidFM ARYA operator software make the FluidFM BOT system the ideal choice for your cutting-edge research applications. QUALITY THROUGH AUTOMATION.

1. Subject to change without notice. Revision: 1.7 ID: CYTO-14-48 Copyright © 2016 Cytosurge AG, Switzerland Redesigned from the ground up, the FluidFM BOT system takes FluidFM technology to the next level. A completely new sample stage design combined with a fully automa- ted measurement head allows new levels of experimental versatility, speed, and precision for FluidFM applications. The revolutionary stage technology employed in the Fluid- FM BOT system sets new benchmarks for long-range sample positioning and opens up a new dimension in your experimental design. FULLY INTEGRATED SYSTEM SOLUTION. F luid FM ® BOT The FluidFM BOT system by Cytosurge provides the most comprehensive FluidFM experience available today. With the FluidFM BOT, users can benefi t from extended automation and a revolutionary sample positioning system. The FluidFM BOT supports the complete range of FluidFM applications, unifi ed in a standalone system. From single cell biology to material sciences, give your research applications the edge with our fl agship product. 60 mm Z-RANGE 0 . 1 n m Z-SENSOR RESOLUTION 240x74 mm SAMPLE AREA 1 n m XY-SENSOR RESOLUTION FluidFM ® A R YA OPERATOR SOFTWARE ANTI-VIBRATION TABLE RECOMMENDED FluidFM ® MICROFLUIDICS CONTROL SYSTEM FluidFM ® BOT XY - STAGE INVERTED OPTICAL MICROSCOPE WITH CAMERA BLISTER PACK BARCODE READER FluidFM ® BOT CONTROLLER FluidFM ® BOT Z - STAGE WITH BOT HEAD ONE PLATFORM, UNIFIED CONTROL.

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