Single Cell Adhesion | Factsheet

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1. CYTOSURGE AG, SÄGEREISTRASSE 25, 8152 GLATTBRUGG, SWITZERLAND PHONE +41 44 533 14 50, FAX +41 44 533 14 59, WWW.CYTOSURGE.COM CONTACT US. We offer complete support for our customers and distributors. Please visit the Cytosurge Help Center in order to access the FluidFM ® user community. www.fluidfm.com SINGLE CELL ADHESION Measuring cellular adhesion at the cell level provides valuable insight for many research topics in biology and medicine. Until now, measuring these inter- actions was highly complex and time consuming. But with FluidFM technology you can boost your research productivity: Gain unpre - cedented insights into organ formation, implant surface proper - ties, and pathogen pathways. F luid FM ® GIVES YOU THE EDGE. Thanks to the unique properties of FluidFM technology you can gather solid cell adhesion data in a short time. Gain access to unparalleled measurement ranges, increasing your experimental flexibility. Reduced pre- paration time in combination with re- usable measurement probes makes FluidFM the perfect tool for all your single cell adhesion studies. GRAB AND MEASURE. Select any adherent cell and detach it using FluidFM. Courtesy of Dörig P., ETH Zurich THE PROCEDURE IN BRIEF. The target cell is selected by the user and then reversibly attached to the FluidFM probe by applying an under- pressure. It is subsequently detached from the surface by retracting the measure - ment probe, and the resulting adhesi - on forces are precisely recorded with pN resolution. All force curves are automatically stored and organized for analysis using our advanced data analysis software or custom third party tools. SELECTED PUBLICATIONS – 2016. J.S. McGrath, J. Quist, J.R.T. Seddon, S.C.S. Lai, S.G. Lemay & H.L. Bridle. Deformability Assessment of Waterborne Protozoa Using a Microfluidic-Enabled Force Microscopy Probe. PloS one, 11(3), e0150438. doi:10.1371/journal. pone.0150438 – 2014. E. Potthoff, D. Franco, V. D’Alessandro, C. Starck, V. Falk, T. Zambelli, J. A. Vorholt, D. Poulikakos & A. Ferrari. Toward a rational design of surface textures promoting endo- thelialization. Nano Letters, 14 (2), 1069 – 1079. doi:10.1021/nl4047398 – 2012. E. Potthoff, O. Guillaume - Gentil, D. Ossola, J. Polesel - Maris, S. LeibundGut - Landmann, T. Zambelli & J. A. Vorholt. Rapid and Serial Quantification of Adhesion Forces of Yeast and Mammalian Cells. PLoS ONE, 7 (12), e52712. doi:10.1371/journal.pone.0052712 10 x HIGHER FORCE RANGE THAN STANDARD METHODS 10 x FASTER THAN STANDARD METHODS pN RESOLUTION F luid FM ® – A WORLD OF APPLICATIONS. Subject to change without notice. Revision: 1.2 ID: CYTO-14-11 Copyright © 2016 Cytosurge AG, Switzerland 30 + CELLS A DAY

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