FLUIDFM NANOSCALE PRECISION
Precision delivery. No compromises.
FluidFM is Cytosurge's proprietary intracellular delivery technology. A hollow cantilever thinner than a cell delivers CRISPR editing machinery directly into the nucleus with precise dosage control, eliminating the variability associated with bulk delivery methods.
Stoichiometric delivery
Exact, controlled injection of RNPs and donor templates into every single cell.
Maximized editing specificity
Precisely controlled reagent concentrations prevent the over-dosing seen in bulk delivery, drastically reducing off-target effects.
Uncompromised cell integrity
Unlike harsh electroporation, only FluidFM preserves the native physiological and morphological state of your cells.
Physiological relevance
You are engineering a model. Toxic delivery methods create survivor cells that no longer faithfully represent the biology you are studying.
Downstream data integrity
Preserves biologically relevant cell models for more reliable downstream assays.
Guaranteed monoclonality
Every clone is derived from a single, visually verified cell. Our dual image based monoclonality proof satisfies regulatory requirements.
WHY CELLEDIT
CellEDIT vs. traditional gene editing approaches
| Capability | CellEDIT (FluidFM) | Electroporation | Lipofection | Viral |
| Dose Control | Precise (pg level) | None | None | — |
| Hard-to-transfect Cells Success | High | Low | None | Moderate |
| Multiplex Reliability | High | Low | Low | Moderate |
| Vector-Free Option | Yes | Yes | Yes | No |
| Nuclear Targeting | Yes | No | No | Yes |
CELLEDIT WORKFLOW
How CellEDIT projects move from design to validated clones
Our gene editing service handles the complexity of sensitive cells so you can focus on downstream research. This standardized, reproducible workflow bypasses biological barriers.
Consultation
Project feasibility and CRISPR design strategy
Cell Pickup
Cell Packaging & Collection
CRISPR Design
Development of an editing strategy
CRISPR Injection
FluidFM delivery of CRIPR RNPs into single cells
Clonal Outgrowth
Single cell seeding and monoclonal outgrowth
Screening
Genotypic screening of targeted edits
Quality Control
Monoclonality, viability, sterility, and mycoplasma testing
Shipment
Cryopreserved clones and project report delivery
PROJECT DELIVERABLES
What's included in a CellEDIT project?
Every CellEDIT project combines expert genome engineering support with validated clones and the documentation needed to move confidently into downstream research
Edited monoclonal clones
Validated clones carrying the intended genetic modification.
Wild-type control clones
Matched controls for downstream experimental comparison.
gRNA design support
Guide RNA design and selection tailored to the intended edit.
Validation report
Comprehensive documentation including sequencing results, monoclonality evidence, and project-specific quality-control data.
GENE EDITING TYPES
Explore CellEDIT solutions
From precise gene knockouts to complex multiplex edits, CellEDIT provides validated genome-engineering solutions for difficult-to-edit cell lines.
Knockout
Multiplex gene editing
Knock-in
Large fragment excision
EDIT TYPES
Explore CellEDIT solutions
From precise gene knockouts to complex multiplex edits, CellEDIT provides validated genome-engineering solutions for difficult-to-edit cell lines.
Knockout
Loss of function edits generated through intra-nuclear CRISPR RNP delivery and confirmed by clonal sequencing of both alleles.
Knock-in
Defined insertions up to approximately 120bp without plasmid or viral integration. Edits are validated by sequencing.
Multiplex gene editing
Simultaneous editing of three or more genes with a single Lacun-3 clone. Each target site is independently verified through clonal sequencing prior to release.
Large fragment excision
Domain or multi-exon deletions up to 4 kilobases, validated by junction PCR to confirm intended deletions without unintended rearrangements.