Direct intra-nuclear delivery
Gene engineering and editing without the limitations of genetic material transport.
Works with any cargo & adherent cell type.
Virus research with FluidFM technology
How FluidFM can help understanding fundamental questions in virus research.
Simplify & accelerate early drug-development
Study a drug effect without complications on its delivery.
Deliver any compound directly into the cell & quantify the injected volume for each single cell.
Unprecedented single cell force spectroscopy
10x faster and easier.
Gain access to unparalleled measurement ranges, increasing your experimental flexibility.
Select which cell you want –
place it where you want.
Easy & cell-friendly isolation.
For adherent and suspension cells. Select a specific cell directly from the culture.
Join our motivated & ambitious team – we have several open positions
FluidFM – Go beyond current technological boundaries
Our patented hollow FluidFM probes with apertures down to 300 nm give rise to more than 12 distinctive FluidFM applications.
Solutions with single cell precision for cell editing, assays and cell isolation.
AFM solutions such as single cell and microbe force spectroscopy measurements enabling 10-fold speed and ease of use.
Novel Approaches to Overcome CRISPR In Vitro Delivery Challenges
Article in European Biopharmaceutical Review by Dr. Paul Monnier, Cytosurge AG. In October Issue “Gene editing & CRISPR”.
Pages 34-37. © Samedan Ltd
Force-Controlled Formation of Dynamic Nanopores
Researchers at ETH Zurich, lead by Morteza Aramesh, have found an elegant way to create nanopores with FluidFM - from 2 to 20 nm. With these they observed single neurons over hours, effectively enabling single cell secretomics.
FluidFM has provided us the chance to detach mammalian cells that were very strongly adhered to the substrate, in a systematic way and without any chemical modification of the cantilever; thus, allowing us to study cell behaviour in their natural state and environment.
FluidFM is a highly versatile tool with huge potential in the field of single-cell studies. The instrument enables us to address several unanswered questions in the epigenetics field by pushing experimental boundaries.
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