Direct intra-nuclear CRISPR delivery.

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Our webinar is showing you how to overcome one of the biggest challenges in gene editing: direct delivery of reagents into the nucleus.

With traditional delivery methods, such as lipofection or electroporation, the success of CRISPR-Cas mediated gene editing is often suboptimal. Conventional methods deliver the reagents indirectly through the cytoplasm to the nucleus leading to poor cell viability and low transfection efficiency rates.

Furthermore, precision editing by Homology Directed Repair (HDR), occurs at even lower ratios. This is especially critical when working with rare or hard-to-transfect cells such as iPSCs, neurons or cardiomyocytes, making genome editing tedious.

 

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