FluidFM® ADD‑ON for AFM systems

Gentle and accurate single-cell injection and cytoplasmic biopsies.

An AFM ADD-ON for precision single-cell manipulation

The FluidFM ADD-ON greatly boosts the performance and application range of atomic force microscopes (AFMs) beyond imaging and force spectroscopy. Take advantage of 10x faster single cell force spectroscopy, create patterns by nanoprinting at sub-micrometer resolution, inject liquids into cells or extract material from them. All possible now with your Bruker and Nanosurf AFM thanks to our FluidFM ADD-ON.

Nano-injection into the nucleus for single-cell transfection.

Nano-extraction of pL cellular content for downstream analysis from the very same cell.

Adhesion measurement in native environment.

Pick and place of individual cells for patterning.

Whether you want to inject into or extract from the nucleus or the cytoplasm of a single cell, the FluidFM ADD-ON ensures the cell viability.

All possible now with your Bruker, and Nanosurf AFM thanks to our FluidFM ADD-ON.

Bruker & JPK BioAFM logos

JPK AFM with a FluidFM ADD-ON

Bruker BioScope Resolve, JPK NanoWizard V, CellHesion, ForceRobot

Learn more

Nanosurf logo

Nanosurf AFM with a FluidFM ADD-ON

Nanosurf DriveAFM
FlexAFM and CoreAFM

Learn more

FluidFM ADD-ON suited for your application.

FluidFM ADD-ON - Applications

CRISPR Gene Engineering

Learn more about the FluidFM technology for precision CRISPR gene engineering.

FluidFM ADD-ON - Applications

Temporal Single Cell Profiling

Gain insights into the potential of FluidFM for Live-seq and temporal transcriptome analysis.

FluidFM ADD-ON - Applications


Measure cell adhesion in your cell native environment.

Interested in a stand-alone AFM system?

FluidFM® ADD‑ON: How it works

FluidFM ADD-ON system parts

  • Custom FluidFM Probe holder assuring safe, tight, and reliable mounting of FluidFM Probes.
  • FluidFM microfluidics control system to aspirate or release liquids through the FluidFM Probe. 
  • Barcode reader to access all relevant probe characteristics, most importantly a unique SEM image of every probe.
  • A dedicated fluorescence camera with a digital cantilever filling assistant.
  • FluidFM CORA software, which gives convenient access and control to all components.
FluidFM ADD-ON set-up
FluidFM probe with different adapters

Optimized FluidFM Probes

Our hollow FluidFM Probes exist in a variety of tip shapes, aperture sizes and mechanical specifications, specifically designed to enable a variety of applications – from mechanobiology, and neuroscience to nanoprinting. The adapter of our FluidFM Probes is tailored to the geometrical and physical requirements of the specific AFM.
More information on FluidFM Probes

Want to know more?

Knowledge Center