Combining the best of Microfluidics, AFM & Biology with FluidFM®
Go beyond in single-cell manipulation with FluidFM
Explore the FluidFM® resources for Life Sciences and Biology
The FluidFM technology addresses the most common challenges encountered in the research by combining the use of the Atomic Force Microscope (AFM) for biology and life science applications. Nowadays, this technology is suited for a broad range of biological applications from single-cell adhesion, neurosciences to virology. The FluidFM technology supported technological innovations in fields such as CRISPR cell line engineering by speeding-up the cell line development with a direct intra-nuclear CRISPR-delivery.
Go straight to: Single-cell Profiling | CRISPR Cell engineering | Mechanobiology | Additional resources
Discover the biological applications where FluidFM makes the difference.
The applications highlighted on this page represent the current fields of research where the FluidFM technology has found a growing interest over the last decade. The versatility of this unique technology resides in the hollow FluidFM Probes. They exist in a variety of tip shapes, aperture sizes and mechanical specifications, specifically designed to enable three basic modes, perfect to tackle any biological application needs.
Single-cell Profiling
Educational resources:
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Temporal single-cell profiling on biopsies taken from living cells
- Biopsies for Temporal Transcriptome Analysis
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In Vitro Disease Modeling with FluidFM
- Next Challenges in Single Cell Lineage Tracing
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An Overview of Transcriptomics
- Evolution of single-cell RNA sequencing: from scRNA-seq to Live-seq
- An introduction to a novel single-cell analysis method: single-cell biopsy
- An overview of single-cell manipulation techniques
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An overview of single-cell extraction
- An overview of single-cell injection
Technical resources:
- Cytoplasmic biopsy collection with the FluidFM OMNIUM Platform
- FluidFM OMNIUM Platform
- FluidFM ADD-ON
- FluidFM Technology
Media & Downloads:
- Research Highlight - Live-seq: Live-cell Sequencing with Single-cell Biopsies
- Blog Article - LUTHOR HD: Pushing the Boundaries of Single Cell Transcriptome Analysis by in vitro mRNA amplification
- On-Demand Webinar Replay - Cytoplasmic Live-Cell Biopsies for Temporal Single-Cell Profiling
CRISPR Cell Line Engineering
Educational resources:
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An overview of gene editing techniques
- An overview of transfection methods
- A Short Guide to CRISPR Cancer Research
- CRISPR & Drug Discovery: A Comprehensive Overview
- A Unique Mammalian Cell Transfection Protocol
- What is a gene editing tool?
- An introduction to CRISPR Gene Editing
- CRISPR Cell Line Engineering Use Cases
Technical resources:
- Introduction to CRISPR Knockout Gene Editing with CellEDIT
- An Overview of CellEDIT' CRISPR Cell Line Development Services
- CellEDIT' CRISPR Cell Line Development Workflow
- CellEDIT's Engineered Cell Lines
Media & Downloads
Mechanobiology
Educational resources:
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An Overview of Cell Adhesion
- An Overview of Single-cell Force Spectroscopy
- Mechanobiology - Use cases
- Mechanobiology with the FluidFM®
Technical Resources:
Media & Downloads
- Automated Adhesion Application note
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Single-cell Adhesion Webinar in collaboration with Nanosurf
Additional resources related to AFM and biological applications
Nanoprinting
Print any pattern at sub-micrometer resolution. With any ink. In liquid & air.
The FluidFM technology: developed by researchers for researchers.
The FluidFM technology was created more than 10 years ago with the first publication appearing in the journal Nanoletters in 2009. Today, the technology represents more than 120 FluidFM installations spread across the globe and count some of the most prestigious corporations and academic institutions to our loyal and very active customer base. In addition, more than 100 high impact publications have been published over the last few years with FluidFM. The Cytosurge team has also designed tools to facilitate biological research with smoother and reliable processes. The CellEdit Quoter allows any researchers to employ Cytosurge's expertise in CRISPR Cell Line Engineering to fasten their research.