FluidFM^® BOT BIO Series

• The patented FluidFM technology has already led to more than 60 high-impact publications.

• Many possible applications:

• • Nano-injection into single cells (of CRISPR, drugs, nanoparticles, ...)

  • • Place your cell culture, select the cells of interest. The system autonomously injects into the selected cells. Process hundreds of cells/hour.

    • With a few clicks, quantify the injected volume within the software.

    • Follow each cells’ fate with fully integrated epi-fluorescence microscopy.

    • Study the dose-response statistics for your injected compound.

  • Isolation of single cells (pick & place, cell sorting, ...)

  • • Isolate cells of your choice from an adherent, confluent culture to a separate well.

    • Create monoclonal colonies or analyze the selected cells with 3rd party systems of your choice.

  • Nano-printing (of biomolecules, biomaterials, nanoparticles, ...)

  • • Print spots, high-density arrays or even complex patterns with nanometer precision, useful for example in biosensing to create protein or DNA arrays.

    • Also Poly-L-Lysine can be nano-printed to create submicron structures which will act as scaffolds for controlled cell growth.

  • Single cell adhesion measurements

• Unlock the full potential using FluidFM nanosyringes, nanopipettes and micropipettes and combine the different applications for unique, unprecedented experiments. Example: Inject cells of your choice, nano-extract cell content to follow their fate, isolate and expand the most promising candidates.

• Largely automated

• Intuitive, simple user interface

• Learn to use in one day

• Reliable, safe and fun - just follow the workflows, reduce repetitive tasks, reduce human errors, replicate past experiments

• Watch live-demos here

• >95% viability for any single cell manipulation

• Higher viability than any other single cell technique

• System with 37°C incubator and optional integrated CO₂ control
  

• Perform any experiment on adherent cell cultures and keep the valuable context information. A unique advantage of FluidFM technology.

Our software records the XY-coordinates of the edited cells and allows the user long-term observation of the modified cells with the desired settings (fluorescence filter, exposure time etc…) or even further manipulation of the same cells. Observe any point of interest and follow how events unfold with multi-channel time-lapses.

• 360° support: Experimental design, data interpretation, …