Direct intra-nuclear CRISPR delivery

A solution to CRISPR’s delivery challenges.

Odoo - Sample 1 for three columns

Higher delivery & HDR efficiency

All CRISPR components are delivered simultaneously and at the right concentration directly into the nucleus. For any cargo & cell type, maintaining high cell viability and paving the way to large genomic editing.

Odoo - Sample 3 for three columns

Optimize off-target effects

As the quantity of injected copies can be calculated, dose/response relationships can be investigated and thus off-target mutations minimized.

4 serial injections into the same cell. Lucifer Yellow was used to calculate the volume of solution injected.

Easy multiplex & stack editing

A FluidFM nanosyringe can be loaded with 100's of different gRNAs. Biology is the limit.

Inject different cocktails at different time points: >95% of cells survive the injection procedure.

Direct delivery with a simple mouse click.

Automated and reproducible injection process with an intuitive user interface.