CellEDIT - CRISPR-Edited A549 Cell Line

Let us support you with a custom, high-quality engineered A549 cell line.

We'll handle the CRISPR engineering of your A549 cells, so you can focus on your research. 


A549 cells are lung carcinoma epithelial cells that are widely used in cancer research and drug discovery. They are the most used human non-small cell lung cancer cell line. These hypotriploid alveolar basal epithelial cells were first derived in 1972 from the cultured pulmonary carcinoma tissue of a 58-year-old Caucasian male.

A549 Cell Line Information

Organism

Human

Tissue Type

Lung

Cell Type

Epithelial

Disease

Carcinoma

Karyotype

Hypotriploid

Donor Information

Age

58

Gender

Male

Ethnicity

Caucasian

A549 Cell Line Applications


 Cancer Research: A549 cells are extensively used to study the biology of non-small cell lung cancer, including tumor growth, metastasis, and the molecular mechanisms underlying cancer progression.

 

 Drug Screening & Development: These cells serve as a standard model for testing the efficacy and toxicity of new anticancer drugs, aiding in the identification and optimization of potential therapeutic compounds.

 

 Toxicology Studies: A549 cells are used to assess the cytotoxic effects of various chemicals, environmental pollutants, and potential therapeutic agents, providing insights into their safety and mechanism of action.

 

 Virology Research: Researchers utilize A549 cells to study viral infections, including the mechanisms of viral entry, replication, and host cell response, as well as to develop and test antiviral drugs.


 Respiratory Disease Research: These cells are employed to investigate respiratory diseases, including chronic obstructive pulmonary disease (COPD) and asthma, helping to understand disease mechanisms and develop new treatments.

 

Related Case Studies


Leverage CellEDIT's expertise to boost your research endeavior. With the CellEDIT workflow, we can support you with custom and monoclonal knockout A549 cell lines suited for your project needs.

CellEDIT Engineered A549 Cell Line - Cytosurge
Efficient on 
Hard-to-transfect cells
CellEDIT Engineered A549 Cell Line - Cytosurge
Vector-free 
direct intra-nuclear delivery
CellEDIT Engineered A549 Cell Line - Cytosurge
Minimized Off-Target

Immortalized Cells

Find out how 
the CellEDIT workflow enabled the generation of 5 monoclonal Hprt  knockout C2C12 cell lines through direct intra-nuclear injection of only 51 cells.

Hard-to-Transfect Cells

Discover how 
the CellEDIT workflow facilitated the production of 3 monoclonal HPRT1 knockout SK-MES-1 cell lines, which are notoriously hard-to-transfect.

Multiplex Gene Editing

Explore how 
the CellEDIT workflow boosted the editing efficiency while preserving cell characteristics and functionality in single and multiple KO CHO-K1 clones.

 Available Edits using CellEDIT Engineered Cells


Knockout

Save time in the lab by boosting your research with CellEDIT. Confidently streamline your drug discovery workflow and investigate gene function with effective CRISPR knockouts.


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Knock-in

Leverage CellEDIT's expertise to increase your research output. Confidently generate disease models to fasten your discoveries. Access Knock-ins CRISPR Cell Lines without sacrificing time.


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 Related Resources

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