CellEDIT - CRISPR-Edited CHO Cell Line
Let us support you with a reliable, high-quality engineered CHO Cell Line.
Spend your time running experiments, not generating your CRISPR-engineered CHO cell line.
We’ll handle the CRISPR editing of your cell line, so you can run your experiment faster and finish your project sooner. The CHO cell line was derived from an ovarian biopsy of an adult female Chinese hamster in 1957 and is widely used in industrial biotechnology and toxicology research.
CHO Cell Line Information
Organism
Animal
Tissue Type
Ovary
Cell Type
Epithelial
Karyotype
Hipodiploid
Donor Information
Age
Adult
Gender
Female
Origin
Cricetulus griseus, hamster, Chinese
CHO Cell Line Applications
Biopharmaceutical Production: CHO cells are the most used mammalian cell lines to produce therapeutic proteins, including monoclonal antibodies, enzymes, and hormones. Their ability to produce high yields of recombinant proteins with human-like post-translational modifications makes them invaluable in the pharmaceutical industry.
Gene Expression Studies: These cells are used to study gene expression, regulation, and the effects of gene editing. Researchers often employ CHO cells to produce and analyze recombinant proteins.
Drug Screening and Toxicology: CHO cells are used in high-throughput screening assays to test the efficacy and toxicity of new drugs. Their stable growth and high productivity make them ideal for these applications.
Vaccine Production: CHO cells are used in the development and production of vaccines, including those for viral diseases. They provide a safe and efficient system for producing viral antigens.
Cell Biology Research: CHO cells serve as a model system for studying various cellular processes, including cell cycle regulation, apoptosis, and signal transduction pathways.
Available Edits using CellEDIT Engineered Cells
Use CellEDIT's expertise to elevate your research performance. Engineered CHO cell lines are widely used in various research and industrial applications due to their robustness, adaptability, and ease of genetic manipulation. Overall, CHO cell lines are a versatile tool in biotechnology and biomedical research, contributing significantly to advancements in drug development, genetic engineering, and therapeutic protein production. With the CellEDIT workflow and within 10 weeks, we can efficiently generate custom engineered CHO cell lines designed to suit your project needs. This is achieved through direct intranuclear injection of Cas RNP’s to target the loci defined by you.
Efficient on
Hard-to-transfect cells
Vector-free
direct intra-nuclear delivery
Minimized Off-Target
Knockout
Save time in the lab by empowering your research with CellEDIT. Confidently streamline your drug discovery workflow and investigate gene function with effective CRISPR knockouts.
Multiplex Editing
At CellEDIT, we provide you with multiplexed cell lines in 10 weeks. The efficiency and gentleness of our vector-free editing through intra-nuclear delivery, makes it an ideal system to perform multiplex gene editing in one go.
Related Resources
Educational
Technical
Introduction to CRISPR Knockout Gene Editing with CellEDIT
An Overview of CellEDIT' CRISPR Cell Line Development Services
CellEDIT' CRISPR Cell Line Development Workflow
CellEDIT's Engineered Cell Lines
CRISPR-Engineered U2OS Cell LineCRISPR-Engineered MDA MB 231 Cell Line
CRISPR-Engineered A549 Cell Line
CRISPR-Edited Hek293 Cell Line
Media & Downloads
On-Demand CellEDIT's CRISPR Cell Line Engineering Webinar
CellEDIT's Application Note n*1 - Introducing the CellEDIT Workflow
CellEDIT's Application Note n*2 - Overcoming the hard-to-transfect cell line hurdle
Open Access Publication featuring CellEDIT: Antony, Justin S., Anabel Migenda Herranz, Tahereh Mohammadian Gol, Susanne Mailand, Paul Monnier, Jennifer Rottenberger, Alicia Roig‐Merino et al. " Accelerated generation of gene-engineered monoclonal CHO cell lines using FluidFM nanoinjection and CRISPR/Cas9" Biotechnology Journal 19, no. 4 (2024): 2300505.