CellEDIT - CRISPR-Edited U2OS Cell Line

Let us support you with reliable, high-quality engineered U2OS cell line.

Focus on your research and let us handle your CRISPR-engineered U2OS cell line.


We’ll handle the CRISPR editing so you can run your experiment faster and finish your project sooner. The U2OS cell line was derived in 1964 from a moderately differentiated tibial sarcoma from a 15-year-old female. The cell line displays epithelial morphology.

U2OS Cell Line Information

Organism

Human

Tissue Type

Bone

Cell Type

Epithelial

Disease

Osteosarcoma

Karyotype

Polyploid 

Donor Information

Age

15

Gender

Female

Ethnicity

Unknown

U2OS Cell Line Applications


 Cancer Research: As a model for studying osteosarcoma, U2OS cells help in understanding cancer biology, mechanisms of tumor development, and progression.

 

 Drug Screening & Development: U2OS cells are used to test the efficacy and toxicity of new anticancer drugs, helping in the identification and optimization of potential therapeutic compounds.

 

 Genetic Studies: These cells are used in gene editing and functional genomics studies to investigate the roles of specific genes and genetic pathways in cell growth and disease.

 

 Signal Transduction Research: U2OS cells are employed to study cellular signaling pathways, particularly those related to cancer cell proliferation and survival.

 

 Cell Cycle & Apoptosis Research: Researchers use U2OS cells to study the regulation of the cell cycle and the mechanisms of programmed cell death (apoptosis), which are crucial for understanding cancer and developing new treatments.

 

Related Case Studies


Tap into CellEDIT's expertise to enhance your research capabilities. Engineered U2OS cell lines provide researchers with critical insights into cancer biology, drug development, genetic functions, and cellular mechanisms. With the CellEDIT workflow, we create custom and monoclonal knockout cell lines through direct intra-nuclear injection, suited for your project needs.

CellEDIT Engineered U2OS Cell Lines - Cytosurge
Efficient on 
Hard-to-transfect cells
CellEDIT Engineered U2OS Cell Lines - Cytosurge
Vector-free 
direct intra-nuclear delivery
CellEDIT Engineered U2OS Cell Lines - Cytosurge
Minimized Off-Target

Immortalized Cells

Learn how 
the CellEDIT workflow was used to generate 5 monoclonal Hprt knockouts in C2C12 cell line through direct intra-nuclear injection of only 51 cells. 

Hard-to-Transfect Cells

Discover how 
the CellEDIT workflow was used to produce 3 monoclonal HPRT1 knockouts in SK-MES-1 cell, a notoriously hard-to-transfect cell line.

Multiplex Gene Editing

Find out how 
the CellEDIT workflow boosted the editing efficiency while preserving cell characteristics and functionality in single and multiple KO CHO-K1 clones.

 Available Edits using CellEDIT Engineered Cells


Knockout

Save time in the lab by powering your research with CellEDIT. Confidently streamline your drug discovery workflow and investigate gene function with effective CRISPR knockouts.


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Knock-in

Leverage CellEDIT's expertise to increase your research output. Confidently generate disease models to fasten your discoveries. Access Knock-ins CRISPR Cell Lines without sacrificing time.


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Schedule A Meeting Now to Use CRISPR-Edited U2OS Cell Lines

 Related Resources