Use Cases: Direct intra-nuclear delivery with FluidFM.


Find out how our FluidFM technology can can help your research.

Explore the benefits     

Transfected cells with FluidFM

Fluorescent CRISPR-Cas9 complexes injected into mouse primary hepatocytes.

Fluorescent CRISPR-Cas9 complexes directly injected into mouse primary hepatocytes.

GFP expression in neurons 24h after nano-injection of plasmids into a mouse primary neuron. Direct nuclear injection with FluidFM.

GFP expression in neurons 24h after nano-injection of plasmids into a mouse primary neuron. Courtesy of Jinan University, Guangzhou, China.

Nuclear and cytoplasmic expression - pEGFP-UHRF1 and pmCherry-TRIM21 (2 plasmids) coinjected into CHO-K1 cells.

pEGFP-UHRF1 and pmCherry-TRIM21 (2 plasmids) coinjected into CHO-K1 cells. The nuclear expression of the human UHRF1 protein is observed (3h post injection), as well as the cytoplasmic expression of the human TRIM21 protein.

Mouse primary hepatocyte injected with CRISPR-Cas9 RNP complexes .

Mouse primary hepatocyte injected with CRISPR-Cas9 RNP complexes.

Webinar with a live demo:

FluidFM: a new approach to CRISPR gene editing

A webinar together with Olympus Life Science and Oxford Global showing you how to overcome one of the biggest challenges in gene editing: direct delivery of CRISPR-Cas complexes into the nucleus.

FluidFM: a new approach to CRISPR gene editing (webinar with live demo)



Selected publications 

Introducing substances, such as genetic vectors, into single cells with FluidFM has been established since several years:

      Optimize off-target effects. Perform straight-forward multiplex editing.

      Learn more about the advantages of the FluidFM BOT BIO Series.